Cardiovascular Epigenetics and Gene Regulation (Keystone Symposia)

Cardiovascular disease (CVD) can cut short an adult life unexpectedly in its prime, and also cause debilitating chronic ill health later in life among an increasingly aging population. It is a significant cause of death worldwide, claiming the lives of 17.9 million annually. Emerging, new discoveries in the fields of epigenetics and epitranscriptomics have opened up refreshing horizons offering new biological perspectives and disease targets; the cross-cutting fields have elucidated modulatable nodal effectors, integrating upstream signals that convey com-mon cellular pathways and mediate fundamental cell state changes in health and disease. For example, by targeting modulatable cell states, these new approaches promise to tackle CVD at its root cause, rather than only delaying disease progression.

Presently, there is a recognized core group of CVD epigenetic and epitranscriptomic re-searchers that focus primarily on myocardial cell types. This meeting aims to integrate this group, with investigators across cardiac and vascular fields, including researchers examining new systemic drivers that are emerging as key contributors of CVD pathophysiology, such as metabolism and inflammation. The program will cover gene expression control, cardiac cell states, diverse histone and nucleic acid modifications, and even their contribution to inter-cellular cross-talk, featuring interdisciplinary groups of scientists that bring diverse per-spectives based on different cellular, organelle or pathways of interest. The focus on under-pinning epigenetic processes will make this symposium unique from other conferences. As the wider biological field of epigenetics is rapidly progressing, with ground-breaking discover-ies exponentially increasing, this symposium will also serve as the platform to invite keynote speakers from outside CVD research, to bring fresh perspectives and techniques to the pro-gram and to the scientific community.

Program

A detailed program can be found at the conference website: https://www.keystonesymposia.org/conferences/conference-listing/meeting?eventid=7009

Organization

The conference is jointly organized by Keystone Symposia and the Volkswagen Foundation. The Scientific Organizers are Federica Accornero (Brown University, USA), Roger Foo (National University of Singapore, Singapore), Enzo Porrello (Murdoch Children's Research Institute, Australia).

Keystone Symposia on Molecular and Cellular Biology is a 501(c)(3) nonprofit organization headquartered in Silverthorne, Colorado, USA that convenes open, peer-reviewed conferences across a broad range of the life sciences. The mission of Keystone Symposia is to serve as a catalyst for the advancement of biomedical and life sciences by connecting scientists within and across disciplines at conferences and workshops held at venues that create an environment conducive to information exchange, generation of new ideas and acceleration of applications that benefit society. Approximately 50-60 conferences take place each year.

Registration

If you want to attend the conference please register through Keystone Symposia's website: https://www.keystonesymposia.org/conferences/conference-listing/meeting?eventid=7009

Language

The conference language is English.