Research into HIV vaccine and pathogenesis has typically involved independent groups and efforts. With the advent of renewed optimism aimed at eradicating the viral reservoir, these arms of HIV research are now increasingly overlapping, with insights to be gained on both fronts. This meeting aims to bring together researchers in the fields of HIV infection, immunity, persistence and eradication to explore findings that can inform these distinct research efforts and ultimately translate to advances in the control and elimination of HIV.
HIV infects more than 36 million individuals worldwide and causes over 1 million deaths annually. Yet despite more than 30 years of research, we lack a vaccine that prevents HIV infection as well as a complete understanding of the mechanisms by which HIV interacts with and ultimately evades eradication by the immune system. Antiretroviral therapies exist that hold the virus in check, but do not eliminate the latent viral reservoir. Thus efforts to block the continued spread of HIV will require a multi-targeted approach: to prevent infection, to treat infection and to eradicate the virus in infected individuals. Yet research on HIV prevention and pathogenesis, or cure, have historically operated on separate tracts, with prevention focusing on immune-mediated interventions, such as vaccines, and cure research focused on molecular modulators of the latent virus. But recent independent observations on the latent reservoir, on viral control elicited in long term non-progressors, on new strategies to block infection and kill infected cells, and on the efficacy of vaccines in animal models have collectively prompted increased awareness of the need to couple the immune system to efforts to both prevent infection and eliminate the viral reservoir in HIV infected individuals.
This meeting aims to highlight advances in HIV research at the intersection of immunity and pathogenesis that lay the groundwork for effective preventive and therapeutic interventions. Speakers will share new findings on vaccine development and neutralizing antibody research, insights into the mechanisms underlying antiviral immunity and maintenance of the viral reservoir, as well as studies that aim to harness these insights to advance therapies from viral reactivation to viral eradication. Increasing our understanding of the biology of the virus within the context of its interaction with the immune system is crucial to inform efforts to control HIV, and it is this junction of research on HIV prevention and eradication that will form the focus of this meeting.
There is no fee for the attendance, but registration is essential. The Conference language is English.
Herrenhausen Symposium "HIV Immunity and Eradication"
November 2-3, 2017
Herrenhausen Palace, Hanover, Germany
The program will begin at 8:55 a.m. November 2 and will close on November 3 around 6:00 p.m.
- Vaccines and Antibodies
- Cure Research
- Viral Reservoirs
- HIV Transmission, Restriction and Pathogenesis
- Viral Immunity
- Lessons and Cohorts
Nelson Michael (U.S. Military HIV Research Program, USA)
(all academic titles have been obmitted)
Marcus Altfeld (The Heinrich Pette Institute - Leibniz Institute for Experimental Virology (HPI), Germany), Monsef Benkirane (French National Centre for Scientific Research, France), Eli Boritz (National Institutes of Health, USA), Persephone Borrow (University of Oxford, UK), Nicola Doria-Rose (NIH, USA), Mike Farzan (The Scripps Research Instiute (TSRI), USA), J. Victor Garcia-Martinez (The University of North Carolina at Chapel Hill, USA), Teunis Geijtenbeek (University of Amsterdam, The Netherlands), Anne Goldfeld (Harvard Medical School, USA), Bonnie Howell (Merck, USA), Frank Kirchhoff (Ulm University Hospital, Germany), Mathias Lichterfeld (Massachusetts General Hospital, USA), David Margolis (The University of North Carolina/The Collaboratory of AIDS Researchers for Eradication (CARE), USA), Nelson Michael (Walter Reed Army Institute of Research (WRAIR), USA), Penny Moore (National Institute for Communicable Diseases), Jo-Ann Passmore (University of Cape Town, South Africa), Louis Picker (Oregon Health & Science University), Christine Rouzioux (Université Paris Decartes), Bill Schief (The Scripps Research Institute and International AIDS Vaccine Initiative (IAVI), USA), Olivier Schwartz (Institute Pasteur, France), Hendrik Streeck (Universitätsklinikum Essen, Germany), Steven Wolinsky (Northwestern University, Feinberg School of Medicine, USA)
Christine Borowski (Nature Medicine, USA)
Tanya Bondar (Nature Medicine, USA)
Alison Farrell (Nature Medicine, USA)
Oliver Grewe (Volkswagen Foundation, Germany)
If you would like to attend the conference, please register by clicking on the registration link in the column on the right. There is no registration fee to attend this event but pre-registration is required.
By registering for this conference, you agree that the contact information you provide may be provided on an attendee list, circulated to attendees of the conference only. You are also aware that the Volkswagen Foundation and Nature Publishing Group will be sharing registration data in order to prepared materials for the conference and so that we may send you important information relevant to your attendance to the conference. Your contact details will not be shared with anyone other than the Volkswagen Foundation, Nature Publishing Group, and with attendees of the meeting.
Please note that registration for the conference does not include accommodation.
Travel Grants and Posters
Registrants are invited to submit abstracts for the presentation of short talks and posters. Travel grants are available for junior researchers. The deadline for abstract submission and the travel grants is August 23, 2017 at 6:00 p.m. EDT. Decisions will be sent in end-August. More information on applying for grants is available here.
If you can no longer attend the meeting, please let us know so that we can offer a spot to another. To cancel either email us or log on to the event portal, click on the event and then click the "Cancel your registration" link on the right hand side.
Venue and public transport
The conference is held at Herrenhausen Palace, a new conference center in Hanover, Germany. You can reach the venue by tram: Take line 4 or 5 and get off at "Herrenhäuser Gärten".