ABGESAGT - PI3-Kinase and PTEN at the Interface of Cell Growth, Vesicular Trafficking and Disease

Beginn: Uhr
Ende: Uhr
Schloss Herrenhausen
Fachpublikum Wissenschaft

MEETING CANCELLED -- The Keystone Symposia conference that was scheduled to occur May 4-7, 2020 in Hannover has been cancelled.

PI3Ks are involved in cell growth etc. This 3d illustration shows a cancer cell in the process of mitosis. (Picture: Christoph Burgstedt - stock.adobe.com)
PI3Ks are involved in cell growth etc. This 3d illustration shows a cancer cell in the process of mitosis. (Picture: Christoph Burgstedt - stock.adobe.com)

General information from the VolkswagenStiftung on their business operations and events taking place in Hannover: https://www.volkswagenstiftung.de/en/news-press/news/corona-virus-business-operations-of-the-volkswagen-foundation-continue-as-usual

The Phosphoinositide 3-Kinase (PI3K) signaling pathway is a main regulator in cell growth, metabolism, and survival and Phosphatase and TENsin homolog (PTEN) is a tumor suppressor gene. This conference integrates three decades of research and development in the PI3K/PTEN field and its progression towards the understanding and treatment of human disease. The discovery of rare human disorders arising from deregulation of the PI3K/PTEN pathway is providing important insights into the organismal biology of this pathway, as well as reviving interest in the repurposing of PI3K pathway inhibitors that were originally under development as anti-cancer agents. In addition, improved strategies to effectively use PI3K inhibitors in cancer are progressing through the clinic, with exciting new opportunities to use PI3K inhibitors in cancer immunotherapy treatment. This conference will cover the mechanism of action of the phosphoinositide lipids, their turnover and their downstream effectors, especially in relation to the class II and III PI3K isoforms, whose cellular and organismal functions are gradually being uncovered. Furthermore, the program will emphasize the emerging evidence for a critical role of the PI3K/PTEN pathway in neuronal biology, immunology and autophagy. This conference brings together basic scientists, drug developers and clinicians under one venue to discuss new paradigms in the field. Thus, this conference will catalyze information exchange and spark collaborations that will foster further scientific progress toward the improvement of human health.

International Conference "PI3-Kinase and PTEN at the Interface of Cell Growth, Vesicular Trafficking and Disease" (Keystone Symposia)
May 4-7, 2020
Herrenhausen Palace, Hanover, Germany


A detailed program can be found at the conference website: www.keystonesymposia.org/20E1

Conference Topics at a glance: 

- Class I PI3K/PTEN Pathway: Signaling Mechanisms
- PI3K and Immune Function
- PTEN and Other Lipid Phosphatases
- PI3K/PTEN in Neuronal and Glial Function
- Class III PI3K / Autophagy / PI3P Effectors
- New Developments in PI3K Research, Disease and Treatment
- Class II PI3Ks
- Mechanism-Based Therapeutic Intervention with PI3K/PTEN-Deregulation


The conference is jointly organized by Keystone Symposia and the Volkswagen Foundation. The Scientific Organizers are Bart Vanhaesebroeck, Volker Haucke and Lori Friedman.

Keystone Symposia on Molecular and Cellular Biology is a 501(c)(3) nonprofit organization headquartered in Silverthorne, Colorado, USA that convenes open, peer-reviewed conferences across a broad range of the life sciences. The mission of Keystone Symposia is to serve as a catalyst for the advancement of biomedical and life sciences by connecting scientists within and across disciplines at conferences and workshops held at venues that create an environment conducive to information exchange, generation of new ideas and acceleration of applications that benefit society. Approximately 50-60 conferences take place each year.


If you want to attend the conference please register through Keystone Symposia's website: www.keystonesymposia.org/20E1


The conference language is English.

Venue and Public Transport

The conference is held at Herrenhausen Palace, a modern conference center in Hanover, Germany. You can reach the venue by tram: Take line 4 or 5 and get off at "Herrenhäuser Gärten".