One Million Genomes. From Discovery to Health (Keystone Symposia)

Herrenhausen Palace
Researchers and Professionals

At a Keystone Symposia conference in Hanover on June 4 - 8, 2018, international experts from science, healthcare and industry will discuss the scientific challenges of human genome sequencing and its impact on healthcare.

Conference centre Herrenhausen Palace, Hanover, Germany (Photo: Eberhard Franke for Volkswagen Foundation)
Conference centre Herrenhausen Palace, Hanover, Germany (Photo: Eberhard Franke for Volkswagen Foundation)

The completion of the Human Genome Project in 2003 has catalyzed innovations in scientific research and in healthcare embodied in the term "precision medicine." Across the globe, many nations are investing in large-scale national sequencing cohort programs, resulting in over one million human genomes sequenced and linked to dense phenotypic and clinical data. This Keystone Symposia conference will bring together scientists and leaders from healthcare and industry to discuss how to maximize the value of that investment for human health. It will assemble a unique and highly interdisciplinary international community to articulate how best to use these data-rich resources to provide novel insights into the biology of disease, tools for the management of patients and population health management strategies. The meeting will highlight challenges and potential solutions for germ-line and somatic sequencing programs and make recommendations for optimizing their impact on global health. The crucial role of free and open sharing and exchange of human variation data from these programs in allowing all of them to interpret novel variants and use them in clinical care will be emphasized. The symposium will focus on various scientific challenges for the field, including implementation science, the scalable data infrastructures and analyses required for impact on discovery and clinical care, and the value proposition for the investments that have been made in national programs. The leading edge of clinical impact of clinical sequencing will be highlighted in sessions on pharmacogenomics, and on developing novel therapeutics.

Keystone Symposia Conference "One Million Genomes: From Discovery to Health"
June 4-8, 2018
Herrenhausen Palace, Hanover, Germany


A detailed program can be found at the conference website:

Conference Topics at a glance 

- Large-Scale National Sequencing Programs: Implementation to Impact
- Somatic Sequencing Programs: Biological Insights and Diagnosis
- Implementation Science for Genomic and Precision Medicine
- International Data Resources Enabling Genomic Medicine
- The Actionable Genome
- The Value Proposition for National Sequencing
- Pharmacogenomics: The Leading Edge of Genomics Impact in Medicine
- Use of Large-Scale Bio-Clinical Resources for Drug Discovery


The conference is jointly organized by Keystone Symposia and the Volkswagen Foundation. The Scientific Organizers are Geoffrey S. Ginsburg (Duke University School of Medicine, USA), Teri Manolio (National Human Genome Research Institute, USA) and Patrick Boon Ooi Tan (Genome Institute of Singapore).

Keystone Symposia on Molecular and Cellular Biology is a 501(c)(3) nonprofit organization headquartered in Silverthorne, Colorado, USA that convenes open, peer-reviewed conferences across a broad range of the life sciences. The mission of Keystone Symposia is to serve as a catalyst for the advancement of biomedical and life sciences by connecting scientists within and across disciplines at conferences and workshops held at venues that create an environment conducive to information exchange, generation of new ideas and acceleration of applications that benefit society. Approximately 50-60 conferences take place each year.


If you want to attend the conference please register through Keystone's website


The conference language is English.

Venue and Public Transport

The conference is held at Herrenhausen Palace, a modern conference center in Hanover, Germany. You can reach the venue by tram: Take line 4 or 5 and get off at "Herrenhäuser Gärten".